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US 2026/0243769 A1Published application
Method for the detection of lung cancer
AssigneeBelgian Volition SRL
InventorsMarielle HERZOG, Julie Alberte Hélène Ghislaine CANDIRACCI, Léa Louise Lorence PAYEN, Sébastien Loïc Guillaume COURAUD
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Abstract
The invention relates to methods of analysing cancer comprising detecting or measuring the level of trimethylation of lysine 27 on histone H3 (H3K27Me3) of a cell-free nucleosome in a body fluid sample obtained from a subject, as well as related uses and kits using said method.
Claims23
A method of analysing cancer in a subject, comprising:
- (i) detecting or measuring the level of trimethylation of lysine 27 on histone H3 (H3K27Me3) of a cell-free nucleosome in a body fluid sample obtained from the subject;
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- (ii) analysing circulating tumour DNA (ctDNA) obtained from the subject for a tumour-associated mutation.
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A kit comprising reagents to detect H3K27Me3 and ctDNA.
Dependencies are inferred from the claim text.