Biosensors and related methods
AssigneeMcMaster University
InventorsTohid Didar, Carlos Filipe, Hannah Mann, Shadman Khan, Akansha Prasad
Life of this patent
Estimating the term…
Abstract
Described herein is a biosensor for detecting the presence of a target molecule in a sample. The biosensor comprises: a polymeric hydrogel; a colorimetric indicator entrapped in the polymeric hydrogel; and an oligonucleotide that crosslinks the polymeric hydrogel, wherein the oligonucleotide is separated in the presence of the target molecule, thereby releasing the colorimetric indicator from the hydrogel.
Claims20
A biosensor for detecting the presence of a target molecule in a sample, the biosensor comprising:
- a polymeric hydrogel;
- a colorimetric indicator entrapped in the polymeric hydrogel;
- and
- an oligonucleotide that crosslinks the polymeric hydrogel, wherein the oligonucleotide is separated in the presence of the target molecule, thereby releasing the colorimetric indicator from the hydrogel.
A method of amplifying DNAzyme signalling in a biosensor that detects a bacteria-specific protein from whole bacteria, the method comprising applying to the sensor a lytic bacteriophage that infects and lyses the bacteria.
Dependencies are inferred from the claim text.