Immune cell-derived secretome
AssigneesAgency for Science, Technology and Research, Singapore Health Services Pte Ltd
InventorWan Yee (Wanyi) Teo (Zhang)
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Abstract
There is provided a composition comprising a secretome obtained by culturing an immune progenitor cell in the presence of an agent that activates the immune cell progenitor to an activated immune cell. Also provided is a composition for use in tissue regeneration, a method of generating a macrophage-derived secretome, a method of screening a drug and a method of culturing a proliferative cell.
Claims22
A composition comprising a secretome obtained by culturing an immune progenitor cell in the presence of an agent that activates the immune progenitor cell to an activated immune cell.
(canceled)
A method of generating a macrophage-derived secretome comprising culturing an immune progenitor cell in the presence of a stimulating agent to thereby generate an activated immune cell population and harvesting the secretome from the generated activated immune cell population.
(canceled)
A method of enhancing or initiating tissue regeneration, the method comprising culturing an immune progenitor cell in the presence of a stimulating agent to thereby generate an activated immune cell population;
- harvesting secretome from the generated activated immune cell population;
- and
- administering the harvested secretome to the tissue in need of tissue regeneration.
Dependencies are inferred from the claim text.