Magnetic rheometry method
AssigneeAalto University Foundation sr
InventorsOssi Arasalo, Arttu Lehtonen, Juho Pokki-Riikonen, Linda Srbova
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Abstract
According to an example aspect of the present invention, there is provided a magnetic microrheometry method for estimating microscale viscoelasticity, the method comprising obtaining a 3D culture matrix comprising magnetic spheres, said magnetic spheres having a sphere diameter, exerting a sinusoidally varying magnetic force using a microrheometer thereby causing sinusoidally varying displacement of the magnetic spheres in the 3D culture matrix, measuring the displacement of said magnetic spheres, and estimating microscale viscoelasticity heterogeneity within the 3D culture matrix based at least on the exerted magnetic force and the measured displacement of said magnetic spheres.
Claims18
A magnetic microrheometry method for estimating microscale microscale viscoelasticity, the method comprising:
- obtaining a 3D culture matrix comprising magnetic spheres, said magnetic spheres having a sphere diameter (Dsphere);
- exerting a sinusoidally varying magnetic force ({circumflex over (F)}sphere) using a microrheometer thereby causing sinusoidally varying displacement of the magnetic spheres in the 3D culture matrix;
- measuring the displacement of said magnetic spheres;
- and
- estimating microscale viscoelasticity heterogeneity within the 3D culture matrix based at least on the exerted magnetic force ({circumflex over (F)}sphere) and the measured displacement of said magnetic spheres.
Dependencies are inferred from the claim text.