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US 2026/0242875 A1Published application
Colorectal cancer detection kit or device, and detection method
AssigneesToray Industries, Inc., National Cancer Center
InventorsSatoko KOZONO, Hitoshi NOBUMASA, Satoshi KONDOU, Hiroko SUDO, Junpei KAWAUCHI, Atsushi OCHIAI, Motohiro KOJIMA
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Abstract
It is intended to provide a kit or a device for the detection of colorectal cancer and a method for detecting colorectal cancer. The present invention provides a kit or a device for the detection of colorectal cancer, comprising a nucleic acid capable of specifically binding to a miRNA in a sample from a subject, and a method for detecting colorectal cancer, comprising measuring the miRNA in vitro.
Claims6
A method for detecting colorectal cancer in a human subject, comprising:
- measuring an expression level of hsa-miR-204-3p in a blood, serum, or plasma sample from the subject,
- comparing the measured expression level of hsa-miR-204-3p to a control expression level for a healthy subject;
- detecting an decreased level of hsa-miR-204-3p in the sample from the subject as compared to the control expression level from the sample from the healthy subject;
- wherein the decreased level of hsa-miR-204-3p indicates that the subject has colorectal cancer;
- and
- wherein the method further comprises treating the subject for the colorectal cancer or performing a diagnostic procedure on the subject with the colorectal cancer;
- wherein the treatment comprises surgery, radiotherapy, chemotherapy or a combination thereof, and
- wherein the diagnostic procedure comprises fecal occult blood, rectal examination, colonoscopy, barium enema, CT, MRI, bone scintigraphy, or a combination thereof.
5 more elements
Dependencies are inferred from the claim text.