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US 2026/0242823 A1Published application
Compositions and methods for modulating factor viii function
OwnerLindsey A. George, Rodney M. Camireinventors
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Abstract
Factor VIII variants and methods of use thereof are disclosed.
Claims35
An adeno-associated virus vector comprising a nucleic acid encoding a Factor VIII (FVIII) variant wherein at least one cleavage site for a serine protease has been mutated.
A Factor VIII (FVIII) variant wherein at least one cleavage site for a serine protease has been mutated.
Dependencies are inferred from the claim text.