Interfering rna for inhibiting b7-h3 gene expression and use thereof
AssigneeJenkem Technology Co., Ltd. (Beijing)
InventorsMai YANG, Meina LIN, Hongli JIA, Qingbin WANG, Xiaomeng CHEN, Xuan ZHAO
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Abstract
The present invention provides an interfering RNA for inhibiting B7-H3 expression, use thereof, and a method for preparing cells with reduced B7-H3 expression. The interfering RNA is siRNA, a target sequence of which comprises nucleotide sequences set forth in SEQ ID NOs: 1-25. The interfering RNA can effectively inhibit B7-H3 gene expression, thus being useful for preventing or treating B7-H3 related diseases.
Claims21
-28. (canceled)
An interfering RNA targeting B7-H3, wherein a target sequence of the interfering RNA comprises a nucleotide sequence set forth in any one or two or more of SEQ ID NOs:
- 1-25.
Dependencies are inferred from the claim text.