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US 2026/0242444 A1Published application
Agonistic interleukin 15 complexes and uses thereof
AssigneeSuzhou Forlong Biotechnology Co., Ltd.
InventorsEn JI, Chunyu WANG
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Abstract
The present disclosure provides agonistic IL-15 complexes that have therapeutic use, and methods for making such proteins. The present disclosure additionally provides methods of treating disease in a subject in need thereof by administering such agonistic IL-15 complexes.
Claims45
A fusion protein comprising an interleukin-15 (IL-15) receptor α sushi domain fused to an Fc monomer, wherein the IL-15 receptor α sushi domain comprises the amino acid sequence of SEQ ID NO:
- 5 and the Fc monomer comprises the amino acid sequence of SEQ ID NO:
- 6.
A fusion protein consisting of the amino acid sequence of SEQ ID NO:
- 1.
A fusion protein consisting of the amino acid sequence of SEQ IED NO:
- 2.
Dependencies are inferred from the claim text.