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US 2026/0242345 A1Published application
Oxadiazole derivative
AssigneeSumitomo Pharma Co., Ltd.
InventorsYoshiaki ISOBE, Tomoyuki TANAKA, Hirotaka MIYACHI
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Abstract
A compound of formula (1) wherein Q1 is halogen atom, Q2 is hydrogen atom, etc., X, Y, and Z are nitrogen atom or oxygen atom, and R1 has a given structure, or a pharmaceutically acceptable salt thereof, and a medicament comprising the compound for treating and/or preventing a disease such as epilepsy.
Claims10
A compound of formula (1):
- or a pharmaceutically acceptable salt thereof, wherein
- Q1 is fluorine or chlorine,
- Q2 is hydrogen,
- X, Y, and Z are the same or different and are nitrogen atom or oxygen atom, provided that the ring containing X, Y, and Z is a heteroaryl wherein any two of X, Y, and Z are nitrogen atom and the other is oxygen atom,
- R1 is the following formula (2) or (3):
- R2 and R3 are taken together with the carbon atom to which they are attached to form C3-6 cycloalkyl which may be substituted with 1 to 3 substituents selected independently from the group consisting of halogen, hydroxy, C1-3 alkyl, and C1-3 alkoxy, or C4-6 saturated hetero ring containing one or two heteroatoms selected independently from nitrogen atom and oxygen atom, said saturated hetero ring may be substituted with 1 to 3 substituents selected independently from the group consisting of halogen, hydroxy, C1-3 alkyl, and C1-3 alkoxy.
3 more elements
Dependencies are inferred from the claim text.