Stem cells for transplantation and manufactauring method therefor
AssigneeNational Center of Neurology and Psychiatry
InventorsTakashi OKADA, Yuko Kasahara, Shinichi Takeda
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Abstract
It is intended to provide MSCs for transplantation that have an improved post-transplantation cell survival rate and engraftment rate and are highly safe with fewer adverse reactions, and a method for conveniently producing MSCs for transplantation having a high cell survival rate and engraftment rate. As means therefor, the present invention provides a stem cell for transplantation comprising an MSC capable of overexpressing IL-10.
Claims14
A method for gene therapy, the method comprising administering to a subject in need thereof a population of human mesenchymal stem cells (hMSCs) and an AAV gene therapy vector.
Dependencies are inferred from the claim text.