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AssigneeHenry Ford Health System
InventorsMichael CHOPP, Dilip K. MOONKA, Zhenggang ZHANG, Louie SEMAAN
Estimating the term…
Some embodiments comprise a method and kit for the treatment and prevention of a cancer the method including the steps of administering a therapeutically effective amount of stressed mammalian extracellular vesicles. In some embodiments, the method may further include administration of at least one adjunct treatment comprising a chemotherapeutic agent, surgical resection or radiation therapy to a subject in need thereof. A kit for the treatment and prevention of a cancer composes a therapeutically effective combination of stressed mammalian exosomes, and at least one of: a chemotherapeutic agent, a dose of a radioactive agent for performing radiation therapy and a surgical device for performing resection surgery of a tumor.
A method for preventing or treating a cancer, the method comprising administering a therapeutically effective amount of stressed mammalian extracellular vesicles derived from hypoxia or oxygen and glucose deprived mammalian cells, to a subject in need thereof.
A method of treating cancer in a subject in need thereof, the method comprising administering a therapeutically effective amount of stressed mammalian exosomes in combination with one or more chemotherapeutic agents.
A stressed mammalian cell derived extracellular vesicle derived from a cell stressed under hypoxic conditions or oxygen and glucose deprivation.
A kit comprising stressed mammalian exosomes, a dose of a chemotherapeutic agent, and a package insert comprising instructions for using the stressed mammalian exosomes and the chemotherapeutic agent in combination to treat a subject with cancer.
Dependencies are inferred from the claim text.