Back to results
US 2026/0240908 A1Published application
Anti-pd-1 chimeric antigen receptor t cells and therapeutic uses thereof
AssigneeFred Hutchinson Cancer Center
InventorKarsten EICHHOLZ
Life of this patent
Estimating the term…
Abstract
The present technology provides chimeric antigen receptors (CARs) targeting programmed death protein 1 (PD-1), host cells (e.g., T cells) that contain and/or express the anti-PD-1 CARs, and methods of using the CAR T cells for treating a variety of diseases including HIV, HIV-associated conditions, cancer, and autoimmune diseases.
Claims71
A chimeric antigen receptor (CAR) comprising a signal peptide, an extracellular binding domain specific to programmed death protein 1 (PD-1), a hinge domain, a transmembrane domain, an intracellular costimulatory domain, and/or an intracellular signaling domain.
Dependencies are inferred from the claim text.