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US 2026/0240213 A1Published application
High load hydrogel compositions
AssigneeSociete des Produits Nestle S.A.
InventorVesselin Danailov MILADINOV
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Abstract
The present invention provides an orally administrable hydrogel composition in a unit dosage form, containing: one or more protein with an isoelectric point of 4.5 or greater; and/or one or more cationic mineral salt; as well as carrageenan and/or low methoxyl amidated pectin; and the composition has a pH in the range of 3.8 to 5.0. The present invention also provides shelf-stable packet or container comprising one or more of the orally administrable hydrogel compositions and a method of manufacturing an orally administrable hydrogel composition in a unit dosage form.
Claims20
1:
- An orally administrable hydrogel composition in a unit dosage form, comprising:
- 15 to 50 wt % of one or more protein with an isoelectric point of 4.5 or greater;
- and/or
- 8 to 50 wt % of one or more cationic mineral salt;
- and
- 1 to 5 wt % carrageenan and/or low methoxyl amidated pectin;
- wherein the composition has a pH in the range of 3.8 to 5.0.
4 more elements
2:
- The hydrogel composition according to claim 1, wherein the one or more protein with an isoelectric point of 4.5 or greater is selected from the group consisting of:
- an animal protein or a hydrolysed version thereof;
- a dairy protein selected from the group consisting of a casein protein, a whey protein, a hydrolysed version thereof, and any combination thereof, and
- a plant protein or a hydrolysed version thereof.
1 more element
3:
- The hydrogel composition according to claim 1, wherein the one or more cationic mineral salt is at least one of a calcium salt or a magnesium salt.
4:
- The hydrogel composition according to claim 1, wherein:
- the one or more protein with an isoelectric point of 4.5 or greater is selected from the group consisting of collagen, whey protein, pea protein, a hydrolysed version thereof, and any combination thereof;
- and/or
- the one or more cationic mineral salt is selected from the group consisting of calcium ascorbate, calcium citrate, magnesium glycinate and magnesium citrate.
1 more element
5:
- The hydrogel composition according to claim 1, further comprising one or more organic acids in an amount of 0.1 to 20 wt %.
6:
- The hydrogel composition according to claim 1, further comprising one or more bulking agent in an amount of 20 to 80 wt %.
7:
- The hydrogel composition according to claim 1, further comprising one or more fatty component selected from the group consisting of a fat, a diglyceride, a monoglyceride and an emulsifier, in an amount of 0.1 to 10 wt %.
8:
- The hydrogel composition according to claim 1, further comprising one or more additional vitamin, mineral or micronutrient.
9:
- The hydrogel composition according to claim 1, wherein the one or more protein with an isoelectric point of 4.5 or greater is present in an amount of 15 to 40 wt %.
10:
- The hydrogel composition according to claim 1, wherein the one or more cationic mineral salt is present in an amount of 8 to 40 wt %.
11:
- The hydrogel composition according to claim 1, wherein the carrageenan and/or low methoxyl amidated pectin is present in an amount of 1 to 3 wt %.
12:
- The hydrogel composition according to claim 1, wherein the composition has a pH in the range of 3.8 to 4.5.
13:
- The hydrogel composition according to claim 7, wherein the one or more fatty component selected from the group consisting of a fat, a diglyceride, a monoglyceride and/or an emulsifier is present in an amount of 1 to 9 wt %.
14:
- The hydrogel composition according to claim 1, wherein the composition is substantially free or free from a fat, a diglyceride, a monoglyceride and/or an emulsifier.
15:
- The hydrogel composition according to claim 1, wherein the composition comprises the one or more protein with an isoelectric point of 4.5 or greater and the one or more cationic mineral salt in a total amount of 23 to 87 wt %.
16:
- The hydrogel composition according to claim 1, wherein the unit dosage form has a weight of 0.5 g to 9 g.
17:
- The hydrogel composition according to claim 1, wherein the composition is stable at 68° C. in a closed container for 3 hours.
18:
- A shelf-stable packet or container comprising one or more of the orally administrable hydrogel compositions according to claim 1.
19:
- A method of manufacturing an orally administrable hydrogel composition in a unit dosage form, the method comprising:
- a) adding to water to form a mixture:
- ai) carrageenan and/or low methoxyl amidated pectin;
- and
- aii) one or more protein with an isoelectric point of 4.5 or greater;
- and/or one or more cationic mineral salt;
- b) partially or fully dissolving the mixture;
- c) ensuring the pH of the dissolved mixture is in the range 3.8 to 5.0;
- d) boiling the mixture;
- e) transferring the boiled mixture to moulds to set;
- and
- f) conditioning the mixture to form a hydrogel composition in a unit dosage form.
9 more elements
20:
- An orally administrable hydrogel composition in a unit dosage form obtained or obtainable by the method according to claim 19.