Method for analyzing organic acid in tissue piece
AssigneesShimadzu Corporation, National University Corporation Kobe University
InventorsKaoru NAKAGAWA, Akiko KUBO
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Abstract
An object of the present invention is to provide a method capable of analyzing components other than an organic acid in addition to the organic acid in a tissue piece. A method for analyzing an organic acid in a tissue piece includes, in order, a derivatization step of derivatizing an organic acid present in a tissue piece by dehydration condensation, a coating step of coating the tissue piece with a matrix having a carboxyl group by a vapor deposition method, and a detection step of performing matrix-assisted laser desorption/ionization mass spectrometry on the tissue piece to detect the derivatized organic acid.
Claims5
A method for analyzing an organic acid in a tissue piece, the method comprising, in order:
- a derivatization step of derivatizing an organic acid present in a tissue piece by dehydration condensation;
- a coating step of coating the tissue piece with a matrix having a carboxyl group by a vapor deposition method;
- and
- a detection step of performing matrix-assisted laser desorption/ionization mass spectrometry on the tissue piece to detect the derivatized organic acid.
Dependencies are inferred from the claim text.