Radioisotope source
AssigneeAdvanCell Pty Limited
InventorsNicolò CANEVER, Julian KELLY, Simon PUTTICK, William TIEU, Kevin KUAN
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Abstract
A layered radioisotope source for generating a medically useful dose of daughter radioisotope through a chain of spontaneous decay from a parent radioisotope via a gaseous intermediate radioisotope, comprising: an inert ceramic substrate layer; a metal oxide surface layer bound on the inert ceramic substrate layer; and parent radioisotope immobilised on or within the metal oxide surface layer to allow for effective emanation of the gaseous intermediate radioisotope away from the layered radioisotope source.
Claims69
A layered radioisotope source for generating a medically useful dose of daughter radioisotope through a chain of spontaneous decay from a parent radioisotope via a gaseous intermediate radioisotope, comprising:
- an inert ceramic substrate layer;
- a metal oxide surface layer bound on the inert ceramic substrate layer;
- and
- parent radioisotope immobilised on or within the metal oxide surface layer to allow for effective emanation of the gaseous intermediate radioisotope away from the layered radioisotope source.
The layered radioisotope source of any one of claims 1 to 28, wherein the parent radioisotope is an alpha-emitting radioisotope.
A sol-gel process for preparing a layered radioisotope source for generating a medically useful dose of daughter radioisotope through a chain of spontaneous decay from a parent radioisotope via a gaseous intermediate radioisotope, comprising:
- a) providing on the surface of an inert ceramic substrate layer a gel formed from a solution (e.g. sol) comprising a metal alkoxide and a parent radioisotope:
- b) heating the gel under conditions effective to form a metal oxide surface layer bound on the inert ceramic substrate layer,
- wherein the parent radioisotope is immobilised on or within the metal oxide surface layer to allow for effective emanation of the gaseous intermediate radioisotope away from the layered radioisotope source.
Dependencies are inferred from the claim text.