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US 2026/0235632 A1Published application
Assay system
AssigneeActome GmbH
InventorCsaba JENEY
Life of this patent
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Abstract
A method of concurrently determining the concentration and/or status of an analyte using pairwise readout of three or more binding agents, where each of said binding agents binds to a different site on the analyte is described. The amount of analyte present is determined by detecting the presence of two or more pairs of binding agents using a bi-component detection method.
Claims8
A method of determining the concentration and/or status of an analyte comprising:
- (a) contacting the analyte with three or more binding agents, wherein each of said binding agents binds to a different site on the analyte and is associated with a unique label;
- (b) detecting the amount of analyte bound by two or more pairs of binding agents using a bi-component detection method;
- (c) determining the concentration and/or status of the analyte present based on the measurements obtain in step (b).
A kit for determining the concentration and/or status of an analyte comprising:
- (a) three or more labelled binding agents, wherein each of said binding agents binds to a different site on the analyte suitable for use in bi-component detection method;
- and
- (b) reagents for detecting pairs of binding agents using a bi-component detection method;
- and/or
- (c) a computer programme which when run on a computer analyses the results of the bi-component detection method and determines the concentration of the analyte in a sample;
- and optionally
- (d) instructions for carrying out the bi-component detection method.
4 more elements
Dependencies are inferred from the claim text.