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US 2026/0235570 A1Published application
Simultaneous detection of a plurality of compounds using dual ionization source
AssigneeShimadzu Corporation
InventorsNitish SURYAWANSHI, Shalu NAIR, Samruddha CHAVAN, Nitin SHUKLA, Jitendra KELKAR, Pratap RASAM
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Abstract
The present disclosure refers to a method of detecting a plurality of compounds in a sample which comprises first ionizing the sample with a first ionization method, and second ionizing the sample with a second ionization method.
Claims10
A method of at least one of a detecting nitrosamine drug substance related impurities (NDSRI) and at least one of a nitrosamine compound from an active pharmaceutical ingredient (API), the method comprising;
- first ionizing the NDSRI with a first ionization method to produce ionized NDSRI,
- second ionizing the nitrosamine compound with a second ionization method to produce ionized nitrosamine compound, and
- detecting the ionized NDSRI and the ionized nitrosamine compound, wherein the first ionization method and the second ionization method are different.
Dependencies are inferred from the claim text.