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US 2026/0235491 A1Published application
Multi-well assay plate system for enhanced flow cytometry and method of use
AssigneeAzure Biosystems, Inc.
InventorsCatalin Pavel, You Chen, Wei Xu, Lilian Sirbu, Lipo Xu
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Abstract
The present disclosure provides flow cytometers, reagent cartridges, multi-well reagent and sample plates, and methods of analyzing a sample by flow cytometry using same.
Claims14
A system for analyzing multiple samples by flow cytometry, the system comprising:
- a sample preparation module comprising:
- a tray configured to accommodate at least one tube containing a sample specimen and a multi-well assay plate,
- a reader configured to capture an identifier code associated with the sample specimen, a sample analyzer configured to analyze sample disposed in the sample preparation module,
- a liquid handler including at least one probe in fluid communication with the sample analyzer and configured to contact the sample specimen, and
- a handler wash module configured to wash the probe before and/or after the probe contacts a sample;
- and
- a processing unit in operative communication with the sample analyzer and configured to control the operation of the sample preparation module, the handler wash module, and the sample analyzer.
4 more elements
A method of analyzing multiple samples by flow cytometry, the method comprising:
- receiving one tube containing sample specimen;
- scanning a first label on said tube;
- receiving a location and a volume associated with the sample specimen;
- receiving a multi-well assay plate;
- scanning a second label on said assay plate;
- loading assay protocol instructions into a processor associated with a flow cytometer system;
- determining, via the assay protocol instructions, if the volume of the sample specimen is sufficient;
- analyzing, if the volume of the sample specimen is sufficient, the sample specimen according to the assay protocol instructions, wherein the analyzing comprises:
- transferring a portion of the sample specimen to a sample analyzer of the flow cytometer;
- collecting, via the flow cytometer, flow cytometry data associated with the portion of the sample specimen;
- processing the flow cytometry data according to the assay protocol instructions;
- and
- outputting the processed flow cytometry data to a user interface associated with the flow cytometer.
10 more elements
Dependencies are inferred from the claim text.