Nucleic acid, recombinant vector, targeted integrated cell, gene expression method, and use

Abstract

A nucleic acid, and a recombinant vector and targeted integrated cell including the same, and a method for producing a target gene expression product and a use thereof are provided. The nucleic acid includes a nucleic acid fragment as shown in SEQ ID NO: 1, and the nucleic acid fragment is used for integrating an exogenous nucleic acid fragment. Upon a large number of cell strain screenings in the early stage, it is found that for the nucleic acid fragment as shown in SEQ ID NO: 1 or a homologous fragment that maintains at least 90% identity with the nucleic acid fragment, an exogenous nucleotide sequence is integrated into the nucleic acid fragment or the homologous fragment thereof.

Dependencies are inferred from the claim text.