De novo designed cyclic oligomeric proteins
AssigneesUniversity of Washington, New York University
InventorsLance Joseph STEWART, David BAKER, Natasha EDMAN, Thomas SCHLICHTHAERLE, Ali ETEMADI, Andrew FAVOR, Wei YANG, Derrick HICKS, Brian COVENTRY, Hannele RUOHOLA-BAKER, Ashish PHAL, Rachel REDLER, Gira BHABHA, Damian EKIERT
Life of this patent
Estimating the term…
Abstract
Polypeptides are provided having an amino acid sequence at least 50% identical to the amino acid sequence selected from SEQ ID NO: 1-19, and cyclic oligomers of such polypeptides.
Claims22
A polypeptide comprising an amino acid sequence at least 50%, 55%, 65%, 70%, 75%, 80%, 85%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99%, or 100% identical to the amino acid sequence selected from the group consisting of SEQ ID NO:1-19, wherein 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, or more, or all of the residue positions listed in Column 4 of Table 1 are conserved relative to the reference polypeptide.
(canceled)
21-22. (canceled)
Dependencies are inferred from the claim text.