Derivatives, immunogens, and antibodies and use of the same in detection of ecstasy-class compounds

A compound corresponding in structure to a Formula (I):

• wherein
• L1 is
• R1 is hydrogen, an alkyl, or —CO(CF3);
• R2 is hydrogen, an alkyl, or —(CH2)b—(X1)—(Y1)c;
• X1 is —SH, —NH2, —COOH, —CONH—, —S(CH2)(CO)NH—, —CO(NH)(C2H4)S(CH2)(CO)NH—, —CO(NH)(C2H4)SH, or
• Y1 is an immunogenic carrier or a label;
• b is 1 to 10;
• c is zero or 1;
• R3 is hydrogen, alkyl, or —(CH2)d—(X2)—(Y2)e;
• X2 is —SH, —NH2, —COOH, —CONH—, —S(CH2)(CO)NH—, —CO(NH)(C2H4)S(CH2)(CO)NH—, or
• Y2 is an immunogenic carrier or a label;
• d is 2 to 12;
• e is zero or 1;
• R4 is hydrogen or —(CH2)f(X3)—(Y3)g;
• X3 is —SH, —NH2, —COOH, —CONH—, —S(CH2)(CO)NH—, —CO(NH)(C2H4)S(CH2)(CO)NH—, or
• Y3 is an immunogenic carrier or a label;
• f is 1 to 12;
• g is zero or 1;
• a is zero or 1;
• L2 is —(CH2)i—(X5)(Y5)j;
• X5 is —SH, —NH2, —COOH, or —S(CH2)(CO)NH—,
• Y5 is an immunogenic carrier or a label;
• i is 1 to 12;
• and
• j is zero or 1;
• wherein when a is zero, R2 is —(CH2)b—(X1)—(Y1)c, b is 1 or 4, X1 is —CONH—, c is 1, Y1 is an immunogenic carrier or a label, R3 is methyl, R4 is hydrogen, then R1 is hydrogen;
• wherein when a is zero, R1 is hydrogen or methyl, R2 is —(CH2)b—(X1)—(Y1)c, X1 is —CONH—, c is 1, Y1 is an immunogenic carrier or a label, R3 is methyl, R4 is hydrogen, then b is 5-10;
• wherein when a is zero, R2 is —(CH2)b—(X1)—(Y1)c, b is 3 or 4, X1 is —COOH, c is zero, R3 is methyl, R4 is hydrogen, then R1 is hydrogen;
• wherein when a is zero, R1 is hydrogen or methyl, R2 is —(CH2)b—(X1)—(Y1)c, X1 is —COOH, c is zero, R3 is methyl, R4 is hydrogen, then b is 5-10;
• and
• wherein at least one of R1, R2, and R3 is neither hydrogen nor an alkyl.