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AssigneeCornell University
InventorsUlrich B. Wiesner, Lawrence Bonassar, Aiyana Fortin
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Therapeutic methods, imaging methods, and inorganic nanotherapeutic imaging agents and inorganic nanoimaging agents. Inorganic nanotherapeutic imaging agents and inorganic nanoimaging agents are used in therapeutic methods and imaging methods. The inorganic nanotherapeutic imaging agents and inorganic nanoimaging agents are, for example, silica or aluminosilicate nanoparticles functionalized with fluorescent group(s), targeting groups, and therapeutic groups. Therapeutic methods can be used to treat and imaging methods can be used to investigate or diagnose inflammatory joint diseases, such as, for example, rheumatoid arthritis, osteoarthritis, or both, in a subject.
A method of treating a subject diagnosed with or suspected of having or with increased risk due to injury of having rheumatoid arthritis and/or osteoarthritis comprising:
An inorganic nanotherapeutic agent comprising one or more targeting group(s) and one or more therapeutic group(s), wherein the one or more targeting group(s) and the one or more therapeutic group(s) are independently disposed on a surface of the inorganic nanotherapeutic agent.
Dependencies are inferred from the claim text.