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US 2026/0232794 A1Published application
Immune Composition Product for Preventing or Treating Varicella Zoster Virus-Related Diseases and Preparation Method Therefor
OwnerJing JIN, Yuanyuan LI +1inventors
InventorsJing JIN, Yuanyuan LI, Yu ZHOU
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Abstract
Provided is a varicella-zoster vaccine. Specifically, the vaccine comprises an immune composition, and the immune composition comprises an antigenic component and a particle protein component. The particle protein component comprises a nanoparticle protein, and the antigenic component and the particle protein component covalently bind to each other by means of a binding peptide 1 and a binding peptide 2 to form an immunogenic complex. Provided is a preparation method for the varicella-zoster vaccine.
Claims21
-10. (canceled)
An immunogenic complex, comprising:
- an antigenic component consisting of a varicella zoster virus (VZV) gE protein or an immunogenic fragment thereof, a linker peptide 1, and a binding peptide 1;
- and
- a particle protein component consisting of a nanoparticle protein, a linker peptide 2, and a binding peptide 2;
- wherein the antigenic component and the particle protein component are covalently bound to each other via the binding peptide 1 and the binding peptide 2.
1 more element
Dependencies are inferred from the claim text.