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US 2026/0232776 A1Published application
Combinations of dendritic cell-based vaccines and checkpoint inhibitors
AssigneeMayo Foundation for Medical Education and Research
InventorsKeith L. Knutson, Matthew S. Block, Allan B. Dietz, Michael P. Gustafson
Life of this patent
Estimating the term…
Abstract
Methods and materials for treating cancer (e.g., ovarian cancer) using a combination of a Th 17 DC vaccine and an immune checkpoint inhibitor are provided herein.
Claims13
A method for treating a mammal having cancer, wherein said method comprises:
- (a) administering, to said mammal, an effective amount of a vaccine composition capable of activating T cells within said mammal to form activated IL-17-secreting T cells that can recognize one or more antigens expressed by said cancer, and
- (b) administering, to said mammal, an effective amount of an immune checkpoint inhibitor (ICI).
Dependencies are inferred from the claim text.