Compositions and methods for treating intestinal microbiome dysbiosis
AssigneeThe Regents of the University of Michigan
InventorPavan Reddy
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Abstract
This invention relates generally to compositions and methods for treating, preventing, and/or ameliorating symptoms characterized with intestinal microbiome dysbiosis through restoring intestinal physiological hypoxia in subjects suffering from intestinal microbiome dysbiosis. In particular, the present invention provides methods for decreasing dysbiosis, restoring the microbiome, and/or increasing recovery of a microbiome (e.g., following a dysbiosis inducing event), by administering pharmaceutical compositions to a subject capable of restoring intestinal physiological hypoxia.
Claims22
A method for treating, preventing and/or ameliorating symptoms related to one or more conditions associated with and/or related to impaired intestinal physiological hypoxia in a human subject comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising one or more agents capable of restoring intestinal physiological hypoxia.
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A kit comprising one or more agents capable of restoring intestinal physiological hypoxia and one or more additional therapeutic agents.
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Dependencies are inferred from the claim text.