Improving glymphatic-lymphatic efflux
AssigneeUniversity of Rochester
InventorsMaiken Nedergaard, Ting Du, Steven A. Goldman
Life of this patent
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Abstract
The present disclosure relates to improving a glymphatic/lymphatic solute efflux from the central nerve system.
Claims22
A method for improving glymphatic-lymphatic efflux from the central nervous system (CNS) of a subject, comprising enhancing the flow rate of a cervical lymphatic vessel (cLV) of the subject.
A method for improving glymphatic-lymphatic efflux from the CNS of a subject, comprising administering to the subject an inhibitor of phosphodiesterase type 5a.
(canceled)
A method for treating a cerebral edema, a traumatic brain injury, a post-traumatic brain injury, or a neurodegenerative disease in a subject in need thereof, comprising administering to the subject an inhibitor of phosphodiesterase type 5a.
22-25. (canceled)
Dependencies are inferred from the claim text.