Nasal Spray for Phosphodiesterase Inhibitors
AssigneeCyrano Therapeutics, Inc.
InventorsRichard GEOFFRION, Ronald KUPPERSMITH
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Abstract
Disclosed herein are methods of treating a chemosensory dysfunction in a subject, comprising intranasally administering to the subject a phosphodiesterase inhibitor or a salt thereof by a nasal spray device. Also disclosed herein are devices and kits for administering phosphodiesterase inhibitors or salts thereof to a subject in need thereof. The nasal spray devices herein deliver a dosage unit that can be used to treat chemosensory dysfunction from a viral infection or another underlying cause of chemosensory dysfunction.
Claims20
A liquid pharmaceutical composition, wherein the liquid pharmaceutical composition comprising:
- about 1.75 or about 3.1 mg/mL theophylline or a pharmaceutically acceptable salt thereof;
- 0.01% to about 0.5% wt/wt of benzalkonium chloride;
- citric acid;
- sodium chloride;
- and
- water.
A liquid pharmaceutical composition, the liquid pharmaceutical composition comprising:
- about 1.75 to 6.25 mg/mL of theophylline or a pharmaceutically acceptable salt thereof;
- about 0.01% to about 0.3% wt/wt of one or more preservatives;
- a buffering agent;
- and
- water.
Dependencies are inferred from the claim text.