Compositions Comprising an Inhibitor of Galectin-3
AssigneeThe University of Liverpool
InventorLu-Gang Yu
Life of this patent
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Abstract
The present disclosure provides a composition comprising a compound of Formula X, or a pharmaceutically acceptable salt thereof, and/or a compound of Formula Y, or a pharmaceutically acceptable salt thereof, and/or a compound of Formula Z, or a pharmaceutically acceptable salt thereof, for use in inhibiting Galectin-3. The composition may be for use in the treatment and/or prevention of a disease, disorder, state or condition wherein inhibiting Galectin-3 would be beneficial for the treatment and/or prevention of the disease, disorder, state or condition. The disease, disorder, state or condition may be cancer, cancer metastasis, fibrosis, inflammation, diabetes and/or one or more other disease, disorder, state or condition affected and/or mediated by Galectin-3.
Claims28
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A method of treating or preventing a disease, disorder, state or condition in a subject for which inhibiting Galectin-3 would be beneficial for the treatment and/or prevention of the disease, disorder, state or condition the method comprising:
- administering an effective amount of a compound of Formula X or a pharmaceutically acceptable salt thereof, and/or a compound of Formula Y or a pharmaceutically acceptable salt thereof, and/or a compound of Formula Z or a pharmaceutically acceptable salt thereof.
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17-29. (canceled)
35-36. (canceled)
A kit consisting of separate packs, packages or amounts of an effective amount of one or more of:
- a compound of Formula X, a compound of Formula Y, a compound of Formula Z, a composition comprising a compound of Formula X, a composition comprising a compound of Formula Y, a composition comprising a compound of Formula Z a composition comprising two or more of a compound of Formula X, a compound of Formula Y or a compound of Formula Z, and/or pharmaceutically acceptable salts or pharmaceutical formulations of any of those, and optionally with an effective amount of a further active ingredient and/or instructions.
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A pharmaceutical composition comprising a compound of Formula X, or a pharmaceutically acceptable salt thereof, and/or a compound of Formula Y, or a pharmaceutically acceptable salt thereof, and/or a compound of Formula Z, or a pharmaceutically acceptable salt thereof, in combination with an anti-tumour agent and/or anti-metastatic agent and/or chemotherapy agent, and/or radiotherapy agent immunotherapeutic agent.
41-46. (canceled)
Dependencies are inferred from the claim text.