US 2026/0232283 A1 · SYSTEMS, METHODS, AND DEVICES FOR SIMULTANEOUS PET-SPECT IMAGING

Abstract

A dual modality system for PET and SPECT includes a first detector module to detect gamma photons for SPECT imaging of a subject from a first position and to generate first output data in response to the detections, a second detector module to detect gamma photons from a second position opposite the first position and to generate second output data in response to the detection, and a computer device in communication with the first detector module and the second detector module. The computer device includes a processor and a memory. The processor is programmed to receive the first output data, receive the second output data, perform SPECT imaging of the subject using the received first output data, and perform PET imaging of the subject using coincidence data from the received first output data and the received second output data.

Claims20

Dependent claims

A dual modality imaging system for positron emission tomography (PET) and single-photon emission computed tomography (SPECT), the system comprising:

a first detector module configured to detect gamma photons for SPECT imaging of a subject from a first position proximate the subject without using a heavy-metal collimator and to generate first output data in response to gamma photons detected by the first detector module;
a second detector module configured to detect gamma photons from a second position proximate the subject opposite the first position and to generate second output data in response to gamma photons detected by the second detector module;
and
a computer device in communication with the first detector module and the second detector module, wherein the computer device comprises at least one processor in communication with at least one memory device, wherein the at least one processor is programmed to:
receive the first output data from the first detector module;
receive the second output data from the second detector module;
perform SPECT imaging of the subject using the received first output data;
and
perform PET imaging of the subject using coincidence data from the received first output data and the received second output data.

6 more elements

A method for positron emission tomography (PET) and single-photon emission computed tomography (SPECT) imaging comprising:

positioning a first detector module to receive first gamma photons from a subject, the first detector module comprising a coded sensor gamma imager module including a spatial-encoding sensor element comprising scintillator material arranged to have a nonuniform structure in at least one dimension and a scintillation crystal layer positioned below the spatial-encoding sensor element;
positioning a second detector module to receive second gamma photons from the subject;
collimating the received first gamma photons using the spatial-encoding sensor element;
detecting the first gamma photons by the spatial-encoding sensor element or by the scintillation crystal layer after the gamma photons pass through the spatial-encoding sensor element;
outputting, to a computing device, first data on the first gamma photons that are detected by the first detector module;
detecting the second gamma photons with the second detector module;
outputting, to the computing device, second data on the second gamma photons that are detected by the second detector module, the second data being synchronized with the first data;
and
one or both of:
reconstructing, by the computing device, a SPECT image based at least in part on the first data;
and
reconstructing, by the computing device, a PET image based at least in part on the first data and the second data.

9 more elements

A method of calibrating a first gamma photon detector module with respect to a second gamma photon detector module comprising:

positioning the first gamma photon detector module opposite the second gamma photon detector module, the first gamma photon detector module including at least a light photon sensor coupled to at least an end of the first gamma photon detector module;
positioning a positron emitting source between the first gamma photon detector module and the second gamma photon detector module at a known first distance from the first gamma photon detector module and a known second distance from the second gamma photon detector module;
recording coincidence events of annihilation gamma photons from the positron source interacting with the first gamma photon detector module, and the second gamma photon detector module;
and
determining timing factors based on the recorded coincidence events, the timing factors include one or more timing offsets for timing correction of the first gamma photon detector module, and one or more weighting factors for deriving trigger times of the coincidence events.

2 more elements

Dependencies are inferred from the claim text.

Systems, methods, and devices for simultaneous pet-spect imaging

Life of this patent

Systems, methods, and devices for simultaneous pet-spect imaging

Life of this patent

Abstract

Claims20