System and method for deconvolution of breast tissue and breast milk cell proportions using reference dna methylation profiles

A system for handling of a library for reference-based deconvolution of breast tissue and/or breast milk DNA methylation data provided in an assay based upon a methylation process comprising:

• a processor assembly that is constructed and arranged to access a library containing information related to an estimate of relative proportions of epithelial cells, endothelial cells, fibroblasts, adipocytes, B cells, CD4+ T cells, CD8+ T cells, NK cells, monocytes, and neutrophils associated with the breast tissue and/or breast milk, and
• wherein the processor assembly is constructed and arranged to apply the library to diagnosis and treatment of a medical condition based upon patient information obtained from a sample of patient breast tissue and/or breast milk.