Enhanced human-computer interaction systems

A system for enhancing human-computer interaction, comprising:

• (A) One or more selectable databases of information on a plurality of chemical compounds wherein the information in the one or more selectable databases alone or in combination comprises chemical, physical and structural information and biological information for each compound;
• (B) A computational device to calculate for compounds selected from one or more of the selectable databases a relative location in a biological parameter space for each of the selected compounds based on biological information for the compound in the database;
• (C) A computational device to calculate for compounds selected from one or more of the selectable databases a relative location in a chemical, physical and/or structural properties parameter space for each of the selected compounds based on chemical, physical and/or structural information for the compound in the database;
• (D) A computational device to display the parameter spaces of (B) and (C) and to map the selected compounds therein;
• (E) One or more computational modules for human-computer interaction effective for users to:
• (a) select databases from which information is to be displayed;
• (b) select compounds to display from each selected database;
• (c) select biological, physical, chemical and/or structural parameter spaces in which compounds will be represented, including spaces based on combinations of the parameters;
• (d) select methods for calculating the location and/or distance of compounds in the parameter spaces;
• (e) adjust parameters of the parameter space, including scales;
• (f) select and display additional information about compounds and
• wherein the location of compounds in the biological parameter space is determined by one or more dissimilarity and/or a similarity metrics.