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US 2026/0226446 A1Published application
Deimmunized lysostaphin and methods of use
AssigneesTrustees of Dartmouth College, Insmed Incorporated
InventorsKarl E. GRISWOLD, Chris BAILEY-KELLOGG, Yoonjoo CHOI, Kristina BLAZANOVIC, Hongliang ZHAO, Deeptak Verma
Life of this patent
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Abstract
Compositions comprising deimmunized lysostaphin and methods of using the same, e.g., to treat microbial infection in or on a subject, are provided.
Claims10
A deimmunized lysostaphin comprising a mutation at one or more of Ser124, Ser122, Asn121, Arg118, Ile99, Lys95, Tyr93, Leu83, Lys46, Ile41, Asn13, or Asn12 of SEQ ID NO:49.
Dependencies are inferred from the claim text.