Recombinant microorganism with regulated activity of manganese import protein and method for producing o-phosphoserine, cysteine or cysteine derivatives using the same
AssigneeCj Cheiljedang Corporation
InventorsHee-jin SIM, Jin Ah RHO, Hwi-Min JUNG, Hyunjin CHO
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Abstract
The present disclosure relates to a recombinant microorganism, in which the activity of a protein having manganese importing activity is regulated, and a method for producing O-phosphoserine, cysteine or cysteine derivatives using the microorganism.
Claims15
An O-phosphoserine-producing recombinant microorganism, in which the activity of MntH protein is enhanced compared to the endogenous activity.
A method for producing O-phosphoserine, comprising culturing an O-phosphoserine-producing recombinant microorganism, in which the activity of MntH protein is enhanced compared to the endogenous activity, in a medium.
A method for producing cysteine or a derivative thereof, comprising:
- a) culturing an O-phosphoserine-producing recombinant microorganism, in which the activity of MntH is enhanced compared to the endogenous activity, in a medium to produce O-phosphoserine or a medium containing O-phosphoserine;
- and
- b) reacting O-phosphoserine produced in step a) or a medium containing the same with a sulfide in the presence of O-phosphoserine sulfhydrylase (OPSS) or a microorganism comprising the same.
(canceled)
Dependencies are inferred from the claim text.