Spherical nanoparticles for improved composite materials
AssigneeStichting Radboud universitair medisch centrum
InventorsSander Cornelis Gerardus Leeuwenburgh, Rong Wang, Lizzy Anne Babs Cuypers
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Abstract
The invention relates to a method for preparing gels with improved mechanical properties, and to components useful in the manufacture of such a gel, and to the manufacture of such components. The gels are robust to mechanical attack and destructive shear, and comprise spherical nanoparticles.
Claims22
Method for producing spherical hydroxyapatite nanoparticles having an average size of 60-500 nm, the method comprising the steps of:
- i) providing an aqueous calcium salt composition comprising calcium acetate;
- ii) providing an aqueous phosphate composition;
- iii) combining the aqueous calcium salt composition with the aqueous phosphate composition to obtain a reaction mixture wherein spherical hydroxyapatite (sHA) nanoparticles are formed;
- and optionally
- iv) purifying the sHA nanoparticles.
Composition comprising spherical hydroxyapatite nanoparticles having an average size of 100-350 nm.
(canceled)
Colloidal composite gel comprising
- i) organic nanoparticles;
- and
- ii) spherical hydroxyapatite nanoparticles.
(canceled)
Dependencies are inferred from the claim text.