Methods for real-time image guided radiation therapy
AssigneeRefleXion Medical, Inc.
InventorsYevgen VORONENKO, Peter Demetri OLCOTT, Debashish PAL, Rostem BASSALOW
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Abstract
Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.
Claims16
(canceled)
A method for generating a segmented fluence map, the method comprising:
- calculating a radiation-firing matrix (RFM) based on location data from a planning PET image of a target region and a prescribed dose to the target region;
- acquiring PET imaging data of the target region in a radiotherapy system, wherein the radiotherapy system comprises one or more PET detectors, a multi-leaf collimator (MLC) and a therapeutic radiation source;
- preprocessing the acquired PET imaging data by removing regions of the acquired PET imaging data that do not correspond with a location of the target region;
- calculating a radiation fluence by applying the RFM to the preprocessed PET imaging data;
- and
- segmenting the calculated radiation fluence into a segmented fluence map, wherein the segmented fluence map comprises MLC positioning instructions and radiation source firing instructions.
Dependencies are inferred from the claim text.