Method to enhance transport across the blood-brain barrier via vasodilation triggered by vibroacoustic therapy and/or other stacked sensory inputs allowing for synergistic benefits with pharmacological treatments for neurological and circulatory diseases
AssigneeKuranda Services LLC
InventorsShawn Leo Gallagher, Delton Leon Hyatt
Life of this patent
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Abstract
Disclosed are methods and systems for improving treatment efficacy of circulatory and neurological disorders. Stacked sensory inputs are used to stimulate vascular endothelium to release nitric oxide, counteract endothelial dysfunction, and promote vasodilation. Combining vibration with administration of one or more therapeutic modalities provides for synergistic effects on treatment of circulatory and neurological disorders.
Claims21
1-20. (canceled)
A method for enhancing therapeutic efficacy in treating a clinical condition, the method comprising:
- administering a vibration therapy to a patient, wherein the vibration therapy comprises applying vibrations at a frequency between about 20 Hz and 250 Hz;
- and
- administering at least one non-vibrational therapeutic modality to the patient within 24 hours of the vibration therapy,
- wherein the combination of vibration therapy and the non-vibrational therapeutic modality produces a synergistic effect in treating the clinical condition.
A system for enhancing therapeutic efficacy in treating a clinical condition, the system comprising:
- a vibration therapy apparatus configured to deliver vibrations at a frequency between about 20 Hz and 250 Hz to a patient;
- and
- a non-vibrational therapeutic modality configured to be administered to the patient within 24 hours of the vibration therapy,
- wherein the system is designed to produce a synergistic effect in treating the clinical condition through the combination of vibration therapy and the non-vibrational therapeutic modality.
A method for improving substance transfer across a physiological barrier, the method comprising:
- administering a vibration therapy to a patient, wherein the vibration therapy comprises applying vibrations at a frequency between about 20 Hz and 250 Hz;
- and
- administering a therapeutic agent to the patient within 24 hours of the vibration therapy,
- wherein the vibration therapy enhances transfer of the therapeutic agent across the physiological barrier.
Dependencies are inferred from the claim text.