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US 2026/0224693 A1Published application
mRNA VACCINE FOR HERPES SIMPLEX VIRUS
AssigneeUniversity of Houston System
InventorsShaun ZHANG, Xinping FU
Life of this patent
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Abstract
This invention relates to an mRNA-based vaccine composition for strains of herpes simplex virus (HSV), such as herpes simplex virus-2 (HSV-2). The mRNA vaccine composition comprises a combination of herpesvirus glycoprotein D (gD) and gB-pf mRNA, either alone or in combination with gE and/or gC mRNA.
Claims16
An immunogenic composition comprising:
- (a) mRNA encoding herpesvirus glycoprotein D or an immunogenic fragment thereof and mRNA encoding herpesvirus glycoprotein B or an immunogenic fragment thereof, wherein the mRNA for herpesvirus glycoprotein B is translated to glycoprotein B in prefusion fixed form;
- and
- (b) optionally, an adjuvant.
Dependencies are inferred from the claim text.