Triple mrna vaccine for preventing feline rhinotracheitis, feline caliciviral disease, and feline panleukopenia, and preparation method thereof

Abstract

The present invention discloses a triple mRNA vaccine for feline rhinotracheitis, feline caliciviral disease, and feline panleukopenia, and a preparation method thereof. The triple mRNA vaccine is prepared by combining an mRNA expressing a feline herpesvirus gB protein, an mRNA expressing a feline herpesvirus gD protein, an mRNA expressing a feline calicivirus VP1 protein, and an mRNA expressing a feline parvovirus VP2 protein with a liposome encapsulation protocol, followed by mixing to prepare the mRNA vaccine. In addition, the vaccine is applied for prophylactic immunization against the feline rhinotracheitis, the feline caliciviral disease, and the feline panleukopenia. The resulting triple mRNA vaccine can effectively activate a specific antibody, and simplifies a vaccination procedure, and can achieve a goal of simultaneously preventing and controlling the feline rhinotracheitis, the feline caliciviral disease, and the feline panleukopenia through a single immunization.

Dependencies are inferred from the claim text.