Multi-antigenic peptide mimics of gonococcal lipo-oligosaccharide (los) epitopes
AssigneeUniversity of Massachusetts
InventorsPeter A. Rice, Michael W. Pennington, Sunita Gulati, Jutamas Shaughnessy, Sanjay Ram
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Abstract
In some aspects, the disclosure relates to compositions of peptide mimics useful in the treatment of Neisseria gonorrhoeae (N. gonorrhoeae). In some embodiments, the peptide mimics are multi-antigenic molecules of a conserved gonococcal lipo-oligosaccharaide (LOS) epitope. In some aspects, the disclosure relates to methods of making peptide mimics for the treatment of N. gonorrhoeae. In some aspects, the disclosure relates to methods of using peptide mimics for the treatment of N. gonorrhoeae.
Claims13
1-22. (canceled)
An peptide mimic of a conserved gonococcal lipo-oligosaccharide (LOS) epitope not found on human blood group antigens, wherein the peptide mimic is capable of inducing in a subject an immune response against the conserved gonococcal LOS epitope.
-42. (canceled)
Dependencies are inferred from the claim text.