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AssigneesInstitute for Research in Biomedicine, Seattle Children's Hospital d/b/a Seattle Children's Research Institute, Schweizerisches Tropen-und Public Health-Institut
InventorsAntonio LANZAVECCHIA, Joshua Hoong Yu TAN, Claudia DAUBENBERGER, Brandon WILDER
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The present invention provides a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, for example for use in a malaria vaccine. The present invention also provides nucleic acids encoding a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, compositions comprising a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1 and antibodies binding to a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1. The antibodies according to the present invention bind specifically to P. falciparum sporozoites and May be used in the treatment and/or prevention of malaria.
A method of preventing and/or treating malaria in a subject, wherein the method comprises administering to a subject in need thereof:
Dependencies are inferred from the claim text.