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US 2026/0224674 A1Published application
Compositions comprising pedf-derived short peptides and mesenchymal stem cells for bone/cartilage regeneration
AssigneeBRIM Biotechnology, Inc.
InventorsFrank Wen-Chi LEE, Huei-Ling CHANG, Ya-Lang HUANG, Chih-Te CHIEN, Sin-Tzu NING, Chih-Hung CHANG, Hsiu-Jung LIAO
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Abstract
A pharmaceutical composition for use in promoting bone/cartilage regeneration, includes a PEDF-derived short peptide (PDSP); and mesenchymal stem cells (MSCs). The PDSP is 14-39 amino acids long. The PDSP has the amino-acid sequence selected from any one of SEQ ID NOs: 1-9. A concentration of the PDSP is about 10-200 μM.
Claims15
A pharmaceutical composition for treating osteoarthritis or promoting bone/cartilage regeneration, comprising a PEDF-derived short peptide (PDSP);
- and mesenchymal stem cells (MSCs).
Dependencies are inferred from the claim text.