Enriched pelargonium graveolens extracts for the treatment of traumatic brain injuries
AssigneesThe State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research, Sheba Impact Ltd.
InventorsAnat ELMANN, Sigal LIRAZ ZALTSMAN, Nativ DUDAI
Life of this patent
Estimating the term…
Abstract
The invention concerns methods and compositions for treating, preventing, or ameliorating traumatic brain injury (TBI), and for improving cognitive function of a subject suffering from TBI, comprising essential oil extracted from Pelargonium graveolens (Pg oil) enriched with a monoterpene or monoterpenoid.
Claims21
-51. (canceled)
A pharmaceutical or nutritional composition for treating, preventing, or ameliorating traumatic brain injury in a subject or for improving cognitive function of a subject suffering from traumatic brain injury, the composition comprising:
- (a) essential oil extracted from Pelargonium graveolens (Pg oil);
- (b) at least one additional monoterpene or monoterpenoid, wherein the final concentration (weight/weight) of said at least one additional monoterpene or monoterpenoid is at least 50% higher than the concentration of said monoterpene or monoterpenoid in the Pg oil;
- and optionally
- (c) one or more physiologically acceptable carriers.
A method of treating, preventing, or ameliorating TBI, or for improving cognitive function of a subject suffering from TBI, the method comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising:
- (a) essential oil extracted from Pelargonium graveolens (Pg oil);
- (b) at least one additional monoterpene or monoterpenoid, wherein the final concentration in the composition (weight/weight) of said at least one additional monoterpene or monoterpenoid is at least 50% higher than the concentration of said monoterpene or monoterpenoid in the Pg oil;
- and optionally
- (c) one or more physiologically acceptable carriers.
A pharmaceutical or nutritional composition for treating, preventing, or ameliorating traumatic brain injury in a subject, the composition comprising:
- (a) essential oil extracted from Pelargonium graveolens (Pg oil);
- (b) at least one exogenous monoterpene or monoterpenoid;
- and optionally
- (c) one or more physiologically acceptable carriers.
Dependencies are inferred from the claim text.