Topical, isotonic compositions for genital use
AssigneeGlyciome, LLC
InventorsJoanna E. Ellington, G. D. Clifton, Rayne Ellington-Lawrence
Life of this patent
Estimating the term…
Abstract
The present disclosure provides compositions and methods for using topical, isotonic compositions comprising a prebiotic oligosaccharide, a metal co-factor, and an essential oil comprising bornyl acetate. The compositions support the genital microbiota and are useful for, for example, hydrating, lubricating, cleaning, and/or decreasing irritation or inflammation of the urogenital and/or anogenital region of a subject, and/or enhancing the beneficial genital microbiota of a subject. Such compositions are useful before, during, and/or after sexual and/or reproductive activity.
Claims21
A topical, isotonic composition comprising:
- (a) a prebiotic oligosaccharide;
- (b) a metal co-factor;
- and
- (c) borneol, pharmaceutically acceptable salts thereof, or prodrugs of any of the foregoing (e.g., ester prodrugs such as bornyl acetate);
- wherein the pH of the composition ranges from about 3.5 to about 8 and the composition is isotonic with semen or cervicovaginal fluids.
10-11. (canceled)
A method of hydrating, conditioning, cleansing or lubricating the urogenital and/or anogenital region of both members of a sexual dyad, wherein the sexual dyad comprises at least one female subject, comprising:
- (a) administering an effective amount of a first topical, isotonic composition to the urogenital and/or anogenital region of either or both members of the sexual dyad during the non-fertile phase of the female subject, wherein the first topical, isotonic composition administered during the non-fertile phase and the first topical, isotonic composition has a pH of about 4.5 and is isotonic with semen,
- (b) administering an effective amount of a second topical, isotonic composition to the urogenital and/or anogenital region of either or both members of the sexual dyad during the fertile phase of the female subject, wherein the topical, isotonic composition administered during the fertile phase has a pH of about 6.8 and is isotonic with cervico-vaginal fluids.
A method of hydrating, conditioning, cleansing or lubricating the urogenital and/or anogenital region of both members of a sexual dyad, wherein the sexual dyad comprises at least one female subject, comprising:
- administering an effective amount of a topical, isotonic composition to the urogenital and/or anogenital region of either or both members of the sexual dyad during the fertile phase of the female subject, wherein the topical, isotonic composition, includes a muco-adhesive, a biofilm inhibitor, an anti-inflammatory compound and a flavonoid antioxidant, administered during the fertile phase has a pH of about 5-6.8 and is isotonic with cervico-vaginal fluids.
Dependencies are inferred from the claim text.