Septal defect occlusion device

An implantable medical device for occluding an opening of a ventricular septal defect of a heart comprising:

• an expandable container defining a cavity therein, wherein the expandable container comprises at least first and second compartments;
• and
• a plurality of expandable beads disposed within the first and second compartments of the cavity of the expandable container and configured to be hydrated to an expanded state,
• wherein the first compartment is selectively filled with a first number of the plurality of expandable beads and the second compartment is selectively filled with a second, lesser number of the plurality of expandable beads.

A method of implanting a medical device in a septum of a heart, the medical device comprising first and second end portions and an intermediate portion between the first and second end portions, wherein the first end portion, the intermediate portion, and the second end portion are arranged along a longitudinal axis of the medical device, the method comprising:

• advancing a catheter coupled to the expandable member towards a ventricular septal defect of the heart while the medical device is in a first, unexpanded state;
• using the catheter, positioning the medical device in the ventricular septal defect with the first end portion extending into the right ventricle and the second end portion extending into the left ventricle;
• advancing a plurality of expandable beads from the catheter into a cavity of the medical device;
• and
• allowing the expandable member to contact fluid and expand from the first state to an expanded second state such that the second end portion in the left ventricle has a cross-sectional area in a plane perpendicular to the longitudinal axis that is larger than the ventricular septal defect, wherein the medical device, in the expanded second state, is asymmetrical with respect to the ventricular septal defect.