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US 2026/0219339 A1Published application
Magnetic particle spectroscopy method and device
AssigneeRegents of the University of Minnesota
InventorsJian-Ping Wang, Vinit Kumar Chugh, Kai Wu
Life of this patent
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Abstract
A method includes separating a bound magnetic nanoparticle (MNP) from an unbound MNP. The bound MNP includes an MNP bound to an analyte, and a surface functionalization including a probe configured to bind to the analyte.
Claims20
A method comprising:
- separating a bound magnetic nanoparticle (MNP) from an unbound MNP, wherein the bound MNP comprises an MNP bound to an analyte,
- wherein the bound MNP comprises a surface functionalization including a probe configured to bind to the analyte.
A separation apparatus comprising:
- a container configured to house a sample comprising a bound magnetic nanoparticle (MNP) and an unbound MNP, wherein the bound MNP comprises an MNP bound to an analyte, wherein the bound MNP comprises a surface functionalization including a probe configured to bind to the analyte, wherein the bound MNP has a hydrodynamic size that is larger than the unbound MNP;
- and
- a separator configured to separate, based on hydrodynamic size, the bound MNP from the unbound MNP.
A magnetic nanoparticle (MNP) test material comprising:
- a surface functionalized MNP comprising a surface functionalization including a probe configured to bind to an analyte;
- and
- a nonmagnetic microstructure configured to bind to the analyte.
Dependencies are inferred from the claim text.