Chromatography device, chromatography system and method for changing chromatographic column

A chromatography device, comprising a column cartridge assembly and a cartridge-changing mechanism,

• wherein the column cartridge assembly comprises a cartridge body and a chromatographic column disposed in the cartridge body, two adapter assemblies are connected to two ends of the chromatographic column via a pipeline, both of the two adapter assemblies extend through a sidewall of the cartridge body, each of the two adapter assemblies is provided with a first channel, and the first channel is in communication with an inside of the chromatographic column,
• the cartridge-changing mechanism comprises a frame and a sample input-output unit provided on the frame, the frame is provided with a positioning assembly, the positioning assembly is configured for positioning the column cartridge assembly,
• the sample input-output unit is provided with two movable sample probes, the two sample probes are connected to the two adapter assemblies, respectively,
• when the column cartridge assembly is positioned on the frame by the positioning assembly, the two sample probes are capable of moving between a first position and a second position, when the two sample probes move to the first position, the two sample probes are capable of extending into the two first channels, so that insides of the two sample probes are in communication with the two first channels, when the two sample probes move to the second position, the two sample probes are capable of separating from two adapter assemblies, so that the chromatographic column of the chromatography device is changed by changing the column cartridge assembly.