Multi-functional protein compositions and methods of making and use thereof
AssigneeThe Texas A&M University System
InventorsQing Sun, Baizhen Gao
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Abstract
Provided here are multi-functional compositions containing an elastin-like-polypeptide (ELP) scaffold containing two or more antigen-binding components or biological response modifiers. These multi-functional compositions can be used for detection or therapeutic treatment of diseases. Provided here are multi-antigen-binding compositions, each containing two or more antigen-binding components coupled by an elastin-like-polypeptide (ELP) scaffold. These multi-antigen-binding compositions can be used for detection or for therapeutic treatment of a disease.
Claims20
A multi-functional composition, the composition comprising an elastin-like-polypeptide (ELP) scaffold containing two or more antigen-binding components or immunomodulatory agents and two or more specific orthogonal protein interaction pairs.
A multi-antigen-binding composition, the composition comprising two or more antigen-binding components coupled to an elastin-like-polypeptide (ELP) scaffold utilizing two or more specific orthogonal protein interaction pairs.
Dependencies are inferred from the claim text.