Cd73 antibody cocktail therapy

A pharmaceutical combination, comprising a first antigen-binding protein that specifically binds to CD73, and a second antigen-binding protein that specifically binds to CD73, wherein the first antigen-binding protein and the second antigen-binding protein have different CD73 antigen-binding epitopes;

• and wherein the first antigen-binding protein comprises HCDR1-3 and LCDR1-3, wherein said HCDR1 comprising the amino acid sequence set forth in SEQ ID NO:
• 3, said HCDR2 comprising the amino acid sequence set forth in SEQ ID NO:
• 2, said HCDR3 comprising the amino acid sequence set forth in SEQ ID NO:
• 1, said LCDR1 comprising the amino acid sequence set forth in SEQ ID NO:
• 13, said LCDR2 comprising the amino acid sequence set forth in SEQ ID NO:
• 12 (WAS) and said LCDR3 comprising the amino acid sequence set forth in SEQ ID NO:
• 11.