Dissociable envelope binding proteins and uses thereof
AssigneeCSL Behring GmbH
InventorsAndreas GILLE, Louis Jerry FABRI
Life of this patent
Estimating the term…
Abstract
The present disclosure relates generally to envelope-binding proteins and their use in methods of producing and/or purifying an enveloped virus from cell culture.
Claims37
An envelope-binding protein comprising one or more low-density lipoprotein receptor (LDLR) domains and a purification tag.
3-5. (canceled)
(canceled)
9-11. (canceled)
13-19. (canceled)
(canceled)
23-24. (canceled)
26-27. (canceled)
30-31. (canceled)
33-36. (canceled)
38-39. (canceled)
(canceled)
43-46. (canceled)
48-49. (canceled)
A method of producing an enveloped virus in a cell culture, the method comprising culturing a cell line in a cell culture medium comprising a protein that specifically binds vesicular stomatitis virus G (VSV-G) pseudotyped virus.
52-58. (canceled)
60-64. (canceled)
66-69. (canceled)
71-72. (canceled)
Dependencies are inferred from the claim text.