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US 2026/0217768 A1Published application
Nanoparticle-nhe3 peptide to treat diarrhea
AssigneeThe Johns Hopkins University
InventorsMark DONOWITZ, Jordan J. GREEN, Nicholas C. ZACHOS, Hannah VAUGHAN
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Abstract
Disclosed are NHE3 mimetic peptides and their conjugates with a reporter molecule or a carboxylated, branched poly(β-amino ester) (PBAE) nanoparticle and their use for treating diarrhea.
Claims24
A peptide having at least about 80% identity with an amino acid sequence selected from SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, and SEQ ID NO:4, or a fragment thereof.
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Dependencies are inferred from the claim text.